LBP 抗体 (AA 166-437)
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北京 101111
Quick Overview for LBP 抗体 (AA 166-437) (ABIN1886097)
抗原
See all LBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 166-437
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 166 and 437 of Human LBP
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- LBP (Lipopolysaccharide Binding Protein (LBP))
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别名
- LBP
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背景
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The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections.Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall.Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses.Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation.This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.[provided by RefSeq]
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分子量
- 53 kDa
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基因ID
- 3929
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NCBI登录号
- NP_004130, NM_004139
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
抗原
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