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ORAI3 抗体 (C-Term)

ORAI3 适用: 人, 大鼠 WB, ELISA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1885517
发货至: 中国
  • 抗原 See all ORAI3 抗体
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    抗原表位
    • 13
    • 10
    • 9
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 23
    • 3
    小鼠
    克隆类型
    • 23
    • 3
    单克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This ORAI3 antibody is un-conjugated
    应用范围
    • 26
    • 17
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunoaffinity chromotography purified IgG
    免疫原
    Raised against a 19 amino acid peptide from near the carboxy terminus of human ORAI3.
    Top Product
    Discover our top product ORAI3 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    -20 °C
    储存方法
    Can be stored at -20 °C, stable for one year.
    有效期
    12 months
  • 抗原
    ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
    别名
    ORAI3 (ORAI3 产品)
    别名
    ORAI3 antibody, TMEM142C antibody, 9930124N15 antibody, BC061259 antibody, Tmem142c antibody, RGD1306538 antibody, ORAI calcium release-activated calcium modulator 3 antibody, ORAI3 antibody, Orai3 antibody
    背景
    Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels.ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC.All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor.However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2.Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2.Larger molecular weight bands are sometimes seen in SDS-PAGE, these may represent post-translationally modified ORAI 3.
    Synonyms: ORAI3 (1B4F1), Transmembrane protein 142C, TMEM142C, Calcium release-activated calcium channel protein 3
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