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ATG4D 抗体 (N-Term)

Name: ATG4D 抗体 (N-Term)
SKU: ABIN1882161
Availability: OutOfStock

This anti-ATG4D antibody (ABIN1882161) is a Rabbit Polyclonal antibody detecting ATG4D in WB, IHC (p). Suitable for Human, Mouse.

Western blot analysis of anti-G4D Pab 1811a in mouse liver and colon tissue lysate. (ATG4D 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ATG4D 抗体 (N-Term))

IHC (p)

G4D Antibody (N-term) 1811a western blot analysis in HL-60 cell line lysates (35 μg/lane). (ATG4D 抗体 (N-Term))

3 images

(7 references)

产品编号 ABIN1882161

发货至: 中国

Datasheet as PDF

Quick Overview for ATG4D 抗体 (N-Term) (ABIN1882161)

抗原

See all ATG4D 抗体

ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This ATG4D antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7563

Discover our top product ATG4D Primary Antibody

抗原表位
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1
AA 14-43, N-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ATG4D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human ATG4D.

亚型

Ig Fraction
anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 441-470), (C-Term) antibody
ATG4D 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7567 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 14-43) antibody
ATG4D 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 381-474) antibody
ATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (C-Term) antibody
ATG4D 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 220-249) antibody
ATG4D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7565 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 227-257) antibody
ATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 326-356) antibody
ATG4D 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11866 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (Center) antibody
ATG4D 适用: 人, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (AA 42-71), (N-Term) antibody
ATG4D 适用: 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB14788 unconjugated

anti-Autophagy related 4D Cysteine Peptidase (ATG4D) (pSer467) antibody
ATG4D 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Williamson, Zhang, Colberg-Poley: "The human cytomegalovirus protein UL37 exon 1 associates with internal lipid rafts." in: Journal of virology, Vol. 85, Issue 5, pp. 2100-11, (2011) (PubMed).

Li, Hou, Wang, Chen, Shao, Yin: "Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7327-38, (2011) (PubMed).

Baehrecke: "Autophagy: dual roles in life and death?" in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 505-10, (2005) (PubMed).

Lum, DeBerardinis, Thompson: "Autophagy in metazoans: cell survival in the land of plenty." in: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 439-48, (2005) (PubMed).

Greenberg: "Degrade or die: a dual function for autophagy in the plant immune response." in: Developmental cell, Vol. 8, Issue 6, pp. 799-801, (2005) (PubMed).

Levine: "Eating oneself and uninvited guests: autophagy-related pathways in cellular defense." in: Cell, Vol. 120, Issue 2, pp. 159-62, (2005) (PubMed).

Shintani, Klionsky: "Autophagy in health and disease: a double-edged sword." in: Science (New York, N.Y.), Vol. 306, Issue 5698, pp. 990-5, (2004) (PubMed).
抗原

ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

别名

ATG4D

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

分子量

52922

NCBI登录号

NP_001268433, NP_116274

UniProt

Q86TL0

途径

Autophagy