XPC 抗体 (N-Term)
Quick Overview for XPC 抗体 (N-Term) (ABIN1882000)
抗原
See all XPC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            抗原表位
- AA 154-183, N-Term
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                                            纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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                                            免疫原
- This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.
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                                            亚型
- Ig Fraction
 
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                                            应用备注
- WB: 1:2000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            有效期
- 6 months
 
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    - 
                                            : "Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer."    in: Cancer research, Vol. 69, Issue 17, pp. 6857-64, (2009)         (PubMed).        
 
 
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                                            : "Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer."    in: Cancer research, Vol. 69, Issue 17, pp. 6857-64, (2009)         (PubMed).        
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    - XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
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                                            别名
- XPC
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                                            背景
- This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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                                            分子量
- 105953
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                                            NCBI登录号
- NP_001139241, NP_004619
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                                            UniProt
- Q01831
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                                            途径
- p53 Pathway, DNA Damage Repair
 抗原
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