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XPC 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects XPC in WB. It exhibits reactivity toward 人.It has been mentioned in 1 publication
产品编号 ABIN1882000
发货至: 中国
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Quick Overview for XPC 抗体 (N-Term) (ABIN1882000)

抗原

See all XPC 抗体
XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

适用

  • 42
  • 4
  • 2
  • 1

宿主

  • 39
  • 7

克隆类型

  • 40
  • 6
多克隆

标记

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  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This XPC antibody is un-conjugated

应用范围

  • 31
  • 23
  • 11
  • 8
  • 8
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  • 1
  • 1
Western Blotting (WB)

克隆位点

RB40964
  • 抗原表位

    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    AA 154-183, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Stern, Lin, Figueroa, Kelsey, Kiltie, Yuan, Matullo, Fletcher, Benhamou, Taylor, Placidi, Zhang, Steineck, Rothman, Kogevinas, Silverman, Malats, Chanock, Wu, Karagas: "Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer." in: Cancer research, Vol. 69, Issue 17, pp. 6857-64, (2009) (PubMed).

  • 抗原

    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

    别名

    XPC

    背景

    This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

    分子量

    105953

    NCBI登录号

    NP_001139241, NP_004619

    UniProt

    Q01831

    途径

    p53 Pathway, DNA Damage Repair
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