(2 references)-
- 抗原 See all UBR1 抗体
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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抗原表位
- AA 245-274, N-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This UBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human UBR1.
- 克隆位点
- RB41861
- 亚型
- Ig Fraction
- Top Product
- Discover our top product UBR1 Primary Antibody
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anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 2-100) antibody
UBR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 722-862) antibodyUBR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 2-100) antibodyUBR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 2-100) antibodyUBR1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4G7 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 801-900) antibodyUBR1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (Internal Region) antibodyUBR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (Internal Region) antibodyUBR1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (AA 396-445) antibodyUBR1 适用: 人, 犬, 兔, 猴, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1) (N-Term) antibodyUBR1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing." in: World journal of gastroenterology : WJG, Vol. 14, Issue 44, pp. 6863-6, (2008) (PubMed).
: "Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of..." in: Molecular pharmacology, Vol. 72, Issue 3, pp. 725-33, (2007) (PubMed).
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: "Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing." in: World journal of gastroenterology : WJG, Vol. 14, Issue 44, pp. 6863-6, (2008) (PubMed).
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- 抗原
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
- 别名
- UBR1 (UBR1 产品)
- 别名
- Dmel\\CG9086 antibody, Ubr1 antibody, UBR1 antibody, JBS antibody, AI504731 antibody, RGD1562326 antibody, Ubr1 ubiquitin ligase antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, E3 ubiquitin-protein ligase ubr-1 antibody, Ubr1 antibody, ubr1 antibody, UBR1 antibody, ubr-1 antibody
- 背景
- The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.
- 分子量
- 200211
- NCBI登录号
- NP_777576
- UniProt
- Q8IWV7
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