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UBR1 产品

(Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008].

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Featured UBR1 Categories

UBR1 抗体

High quality antibodies with extensive validation data.

UBR1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

UBR1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended UBR1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
Cat. No. ABIN566929
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7151293
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN566928
Quantity 50 μL
Datasheet Datasheet

Recommended UBR1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971040
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960348
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6222994
Quantity 96 tests
Datasheet Datasheet

Recommended UBR1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324468
Quantity 10 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2751876
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our UBR1 Products

Eldeeb, Fahlman: "Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase." in: The Journal of biological chemistry, Vol. 291, Issue 43, pp. 22757-22768, (2016) (PubMed).

Yamaguchi, Moritani, Tanahashi, Osabe, Nomura, Fujita, Keshavarz, Kunika, Nakamura, Yoshikawa, Ichiishi, Shiota, Yasui, Inoue, Itakura: "Lack of association of genetic variation in chromosome region 15q14-22.1 with type 2 diabetes in a Japanese population." in: BMC medical genetics, Vol. 9, pp. 22, (2008) (PubMed).

Ozawa, Nakao, Kurihara, Shimazaki, Shimmura, Ishida, Yoshimura, Tsubota, Okano: "Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation." in: The Journal of biological chemistry, Vol. 283, Issue 36, pp. 24561-70, (2008) (PubMed).

Alkhouri, Kaplan, Kay, Shealy, Crowe, Bauhuber, Zenker: "Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing." in: World journal of gastroenterology : WJG, Vol. 14, Issue 44, pp. 6863-6, (2008) (PubMed).

Wei, Lin, Yang, Wang, Chang, Chen, Chen et al.: "Thiazolidinediones modulate the expression of beta-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of..." in: Molecular pharmacology, Vol. 72, Issue 3, pp. 725-33, (2007) (PubMed).

Synonyms and alternative names related to UBR1

Ubr1 ubiquitin ligase (Ubr1), ubiquitin protein ligase E3 component n-recognin 1 (ubr1), ubiquitin protein ligase E3 component n-recognin 1 (UBR1), E3 ubiquitin-protein ligase ubr-1 (ubr-1), ubiquitin protein ligase E3 component n-recognin 1 (Ubr1), AI504731, Dmel\\CG9086, JBS, RGD1562326, Ubr1, UBR1

Protein level used designations for UBR1

  • CG9086-PA
  • CG9086-PB
  • ubiquitin protein ligase E3 component n-recognin 1
  • E3 ubiquitin-protein ligase UBR1
  • E3a ligase
  • N-recognin-1
  • ubiquitin ligase E3 alpha-I
  • ubiquitin-protein ligase E3-alpha
  • ubiquitin-protein ligase E3-alpha-1
  • ubiquitin-protein ligase E3-alpha-I
  • E3 alpha
  • ubiquitin-protein ligase e3 componen n-recognin
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