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SDHB 抗体 (C-Term)

SDHB 适用: 人 WB 宿主: 兔 Polyclonal RB41925 unconjugated
产品编号 ABIN1881781
发货至: 中国
  • 抗原 See all SDHB 抗体
    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
    抗原表位
    • 16
    • 10
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 205-234, C-Term
    适用
    • 77
    • 33
    • 22
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 73
    • 4
    • 2
    克隆类型
    • 64
    • 15
    多克隆
    标记
    • 38
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SDHB antibody is un-conjugated
    应用范围
    • 60
    • 27
    • 18
    • 13
    • 13
    • 10
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    预测反应
    B, M, Pig
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SDHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human SDHB.
    克隆位点
    RB41925
    亚型
    Ig Fraction
    Top Product
    Discover our top product SDHB Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Ho, Morrison, Silva, Coomber: "The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression." in: Bioscience reports, Vol. 36, Issue 1, pp. e00299, (2016) (PubMed).

    Boominathan, Vanhoozer, Basisty, Powers, Crampton, Wang, Friedricks, Schilling, Brand, OConnor: "Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant." in: Nucleic acids research, Vol. 44, Issue 19, pp. 9342-9357, (2016) (PubMed).

    Cerecer-Gil, Figuera, Llamas, Lara, Escamilla, Ramos, Estrada, Hussain, Gaal, Korpershoek, de Krijger, Dinjens, Devilee, Bayley: "Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 16, pp. 4148-54, (2010) (PubMed).

    Hes, Weiss, Woortman, de Miranda, van Bunderen, Bonsing, Stokkel, Morreau, Romijn, Jansen, Vriends, Bayley, Corssmit: "Low penetrance of a SDHB mutation in a large Dutch paraganglioma family." in: BMC medical genetics, Vol. 11, pp. 92, (2010) (PubMed).

    Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • 抗原
    SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
    别名
    SDHB (SDHB 产品)
    别名
    succinate dehydrogenase 2-3 antibody, CG3283 antibody, Dmel\\CG3283 antibody, Ip antibody, SDH antibody, SDH-IP antibody, SDH-Ip antibody, SDHb antibody, sdhB antibody, CWS2 antibody, IP antibody, PGL4 antibody, SDH1 antibody, SDH2 antibody, SDHIP antibody, 0710008N11Rik antibody, fj46d06 antibody, wu:fj46d06 antibody, succinate dehydrogenase complex iron sulfur subunit B antibody, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 antibody, Succinate dehydrogenase, subunit B (iron-sulfur) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) antibody, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog antibody, SDHB antibody, SDH2-3 antibody, SdhB antibody, sdhb antibody, Sdhb antibody, sdhb.S antibody
    背景
    Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
    分子量
    31630
    NCBI登录号
    NP_002991
    UniProt
    P21912
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