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c-MET 抗体

This anti-c-MET antibody is a 兔 多克隆 antibody detecting c-MET in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881539
发货至: 中国

Quick Overview for c-MET 抗体 (ABIN1881539)

抗原

See all c-MET (MET) 抗体
c-MET (MET) (Met Proto-Oncogene (MET))

适用

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宿主

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克隆类型

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多克隆

标记

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This c-MET antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB17704
  • 纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ZNF593 antibody is generated from rabbits immunized with a His fusion protein from human MET.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Holgren, Dougherty, Edwin, Cerasi, Taylor, Fichera, Joseph, Bissonnette, Khare: "Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: sprouty/c-Met upregulation in human colonic adenocarcinomas." in: Oncogene, Vol. 29, Issue 38, pp. 5241-53, (2010) (PubMed).

    Song, Li, Tretiakova, Salgia, Cagle, Husain: "Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung." in: Archives of pathology & laboratory medicine, Vol. 134, Issue 11, pp. 1702-5, (2010) (PubMed).

    Thanseem, Nakamura, Miyachi, Toyota, Yamada, Tsujii, Tsuchiya, Anitha, Iwayama, Yamada, Hattori, Matsuzaki, Matsumoto, Iwata, Suzuki, Suda, Kawai, Sugihara, Takebayashi, Takei, Ichikawa, Sugiyama et al.: "Further evidence for the role of MET in autism susceptibility. ..." in: Neuroscience research, Vol. 68, Issue 2, pp. 137-41, (2010) (PubMed).

    Sugiura, Kawaguchi, Soejima, Katsumata, Gono, Baba, Kawamoto, Murakawa, Yamanaka, Hara: "Increased HGF and c-Met in muscle tissues of polymyositis and dermatomyositis patients: beneficial roles of HGF in muscle regeneration." in: Clinical immunology (Orlando, Fla.), Vol. 136, Issue 3, pp. 387-99, (2010) (PubMed).

    Tyner, Fletcher, Wang, Yang, Rutenberg-Schoenberg, Beadling, Mori, Heinrich, Deininger, Druker, Loriaux: "MET receptor sequence variants R970C and T992I lack transforming capacity." in: Cancer research, Vol. 70, Issue 15, pp. 6233-7, (2010) (PubMed).

  • 抗原

    c-MET (MET) (Met Proto-Oncogene (MET))

    别名

    MET

    背景

    The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    155541

    NCBI登录号

    NP_000236, NP_001120972

    UniProt

    P08581

    途径

    RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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