BAD 抗体 (pSer124)
(2 references)Quick Overview for BAD 抗体 (pSer124) (ABIN1881098)
抗原
See all BAD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer124
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S124 of human BAD.
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亚型
- Ig Fraction
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anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 101-204) antibody
BAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1G5B3 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 69-168) antibodyBAD 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3H8 unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer136) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer155) antibodyBAD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 92-127) antibodyBAD 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer99) antibodyBAD 适用: 人 ELISA, IHC, DB, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 1-168) antibodyBAD 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Agonist of Cell Death (BAD) (AA 53-81) antibodyBAD 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB06939 unconjugated
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma." in: Molecular cancer research : MCR, Vol. 8, Issue 8, pp. 1116-25, (2010) (PubMed).
: "Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivity." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 107, (2010) (PubMed).
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: "BAD, a proapoptotic member of the BCL2 family, is a potential therapeutic target in hepatocellular carcinoma." in: Molecular cancer research : MCR, Vol. 8, Issue 8, pp. 1116-25, (2010) (PubMed).
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- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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别名
- BAD
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背景
- The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
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分子量
- 18392
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NCBI登录号
- NP_004313, NP_116784
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UniProt
- Q92934
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途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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