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BAD 抗体 (pSer96)

BAD 适用: 小鼠 DB 宿主: 兔 Polyclonal RB40701 unconjugated
产品编号 ABIN1881096
发货至: 中国
  • 抗原 See all BAD 抗体
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    抗原表位
    • 34
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    • 15
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    pSer96
    适用
    • 384
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    • 2
    • 1
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    小鼠
    宿主
    • 459
    • 15
    • 1
    克隆类型
    • 441
    • 34
    多克隆
    标记
    • 180
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    This BAD antibody is un-conjugated
    应用范围
    • 258
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    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S96 of mouse BAD.
    克隆位点
    RB40701
    亚型
    Ig Fraction
    Top Product
    Discover our top product BAD Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Kim, Xin, Moioli, Chung, Lee, Chen, Fu, Koch, Mao: "Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing." in: Tissue engineering. Part A, Vol. 16, Issue 10, pp. 3023-31, (2010) (PubMed).

    Frenzel, Labi, Chmelewskij, Ploner, Geley, Fiegl, Tzankov, Villunger: "Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad." in: Blood, Vol. 115, Issue 5, pp. 995-1005, (2010) (PubMed).

    Quoyer, Longuet, Broca, Linck, Costes, Varin, Bockaert, Bertrand, Dalle: "GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells." in: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1989-2002, (2010) (PubMed).

    Wu, Wang, Schroer, Choi, Chen, Okada, Woo: "Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice." in: Diabetologia, Vol. 52, Issue 10, pp. 2130-41, (2009) (PubMed).

    Polzien, Baljuls, Rennefahrt, Fischer, Schmitz, Zahedi, Sickmann, Metz, Albert, Benz, Hekman, Rapp: "Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28004-20, (2009) (PubMed).

  • 抗原
    BAD (BCL2-Associated Agonist of Cell Death (BAD))
    别名
    BAD (BAD 产品)
    别名
    bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
    背景
    BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
    分子量
    22080
    NCBI登录号
    NP_031548
    UniProt
    Q61337
    途径
    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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