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BAD 抗体 (pSer96)

Cited in 5+ publications. This anti-BAD antibody is a 兔 多克隆 antibody detecting BAD in DB. Suitable for 小鼠.
产品编号 ABIN1881096
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BAD 抗体 (pSer96) (ABIN1881096)

抗原

See all BAD 抗体
BAD (BCL2-Associated Agonist of Cell Death (BAD))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This BAD antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB40701
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    pSer96

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S96 of mouse BAD.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kim, Xin, Moioli, Chung, Lee, Chen, Fu, Koch, Mao: "Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing." in: Tissue engineering. Part A, Vol. 16, Issue 10, pp. 3023-31, (2010) (PubMed).

    Frenzel, Labi, Chmelewskij, Ploner, Geley, Fiegl, Tzankov, Villunger: "Suppression of B-cell lymphomagenesis by the BH3-only proteins Bmf and Bad." in: Blood, Vol. 115, Issue 5, pp. 995-1005, (2010) (PubMed).

    Quoyer, Longuet, Broca, Linck, Costes, Varin, Bockaert, Bertrand, Dalle: "GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells." in: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1989-2002, (2010) (PubMed).

    Wu, Wang, Schroer, Choi, Chen, Okada, Woo: "Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice." in: Diabetologia, Vol. 52, Issue 10, pp. 2130-41, (2009) (PubMed).

    Polzien, Baljuls, Rennefahrt, Fischer, Schmitz, Zahedi, Sickmann, Metz, Albert, Benz, Hekman, Rapp: "Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation." in: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28004-20, (2009) (PubMed).

  • 抗原

    BAD (BCL2-Associated Agonist of Cell Death (BAD))

    别名

    BAD

    背景

    BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

    分子量

    22080

    NCBI登录号

    NP_031548

    UniProt

    Q61337

    途径

    MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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