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VAV1 抗体 (AA 121-324)

VAV1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN1845807
发货至: 中国
  • 抗原 See all VAV1 抗体
    VAV1 (Vav 1 Oncogene (VAV1))
    抗原表位
    • 15
    • 11
    • 10
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-324
    适用
    • 70
    • 39
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 68
    • 4
    小鼠
    克隆类型
    • 68
    • 4
    单克隆
    标记
    • 41
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    This VAV1 antibody is un-conjugated
    应用范围
    • 47
    • 34
    • 12
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human VAV1 (AA: 121-324) expressed in E. Coli.
    亚型
    IgG1
    Top Product
    Discover our top product VAV1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原
    VAV1 (Vav 1 Oncogene (VAV1))
    别名
    VAV1 (VAV1 产品)
    别名
    VAV antibody, Vav antibody, vav-T antibody, vav guanine nucleotide exchange factor 1 antibody, vav 1 oncogene antibody, vav guanine nucleotide exchange factor 1 L homeolog antibody, VAV1 antibody, Vav1 antibody, vav1.L antibody
    背景
    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.
    分子量
    98.3 kDa
    基因ID
    7409
    UniProt
    P15498
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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