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CLEC7A 抗体 (PE)

CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal BD6 PE
产品编号 ABIN1820010
发货至: 中国
  • 抗原 See all CLEC7A 抗体
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    适用
    • 54
    • 36
    • 6
    • 1
    宿主
    • 40
    • 17
    • 15
    小鼠
    克隆类型
    • 41
    • 26
    单克隆
    标记
    • 24
    • 10
    • 8
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    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CLEC7A antibody is conjugated to PE
    应用范围
    • 41
    • 37
    • 23
    • 22
    • 9
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
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    Flow Cytometry (FACS)
    特异性
    Recognizes human Dectin-1, also known as beta-glucan receptor (GR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (GR-A and GR-B) and several minor isoforms. GR-A and GR-B differs by the presence and absence, respectively, of a stalk region. Clone BD6 recognizes GR-A only.
    纯化方法
    Protein G purified
    免疫原
    NIH3T3 cells expressing full length Beta-glucan receptor.
    克隆位点
    BD6
    亚型
    IgG2b
    Top Product
    Discover our top product CLEC7A Primary Antibody
  • 应用备注
    Approved: Flo (1:1)

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    Distilled water
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Protect from light.
    储存条件
    4 °C
    储存方法
    Store at 4°C. Do not freeze. Protect from light.
  • 抗原
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    别名
    CLEC7A / Dectin 1 (CLEC7A 产品)
    别名
    CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
    背景
    Name/Gene ID: CLEC7A

    Synonyms: CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1
    基因ID
    64581
    UniProt
    Q9BXN2
    途径
    Activation of Innate immune Response
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