CLEC7A 抗体
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- 抗原 See all CLEC7A 抗体
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CLEC7A antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- Recognizes human Dectin-1, also known as beta-glucan receptor (GR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (GR-A and GR-B) and several minor isoforms. GR-A and GR-B differs by the presence and absence, respectively, of a stalk region. The antibody (clone GE2) recognizes both of these isoforms. Clone GE2 could be used to inhibit receptor function.
- 纯化方法
- Protein G purified
- 内毒素水平
- Low Endotoxin
- 免疫原
- NIH3T3 cells expressing full length Beta-glucan receptor.
- 克隆位点
- GE2
- 亚型
- IgG1
- Top Product
- Discover our top product CLEC7A Primary Antibody
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anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 66-247) antibody
CLEC7A 适用: 人 FACS, WB, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 4G2G6 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 41-140) antibodyCLEC7A 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-44) antibodyCLEC7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibodyCLEC7A 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal 15E2 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibody (APC)CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal 15E2 APC
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibody (PE)CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal 15E2 PE
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 36-127) antibodyCLEC7A 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 70-98), (N-Term) antibodyCLEC7A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB30231 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (Middle Region) antibodyCLEC7A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Approved: Flo (1:1 - 1:25), Func
Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze-thaw cycles.
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- 抗原
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- 别名
- CLEC7A / Dectin 1 (CLEC7A 产品)
- 别名
- CLEC7A antibody, BGR antibody, Clecsf12 antibody, beta-GR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, Clec7b antibody, RGD1565140 antibody, C-type lectin domain containing 7A antibody, C-type lectin domain family 7, member a antibody, CLEC7A antibody, Clec7a antibody
- 背景
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Name/Gene ID: CLEC7A
Synonyms: CLEC7A, BGR, CANDF4, CLECSF12, Dectin-1, DC-associated C-type lectin 1, DECTIN1, HDectin-1, Beta-glucan receptor, Lectin-like receptor 1 - 基因ID
- 64581
- 途径
- Activation of Innate immune Response
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