TNFRSF12A 抗体 (PE)
-
- 抗原 See all TNFRSF12A 抗体
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TNFRSF12A antibody is conjugated to PE
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Recognizes human CD266, otherwise known as Fn14/TWEAK Receptor, a 14kD type I transmembrane glycoprotein and member of the tumor necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumors. The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumor cell lines is mediated by CD266, see for details. Clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 cells in flow cytometry.
- 纯化方法
- Protein G purified
- 免疫原
-
Human CD266 transfected P815 cells.
Type of Immunogen: Cells - 克隆位点
- ITEM-4
- 亚型
- IgG2b
- Top Product
- Discover our top product TNFRSF12A Primary Antibody
-
-
- 应用备注
-
Approved: Flo, IHC, IHC-Fr, WB
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - 说明
-
Target Species of Antibody: Human
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
- Distilled water
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze. Protect from light.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze. Protect from light.
-
- 抗原
- TNFRSF12A (Tumor Necrosis Factor Receptor Superfamily, Member 12A (TNFRSF12A))
- 别名
- TNFRSF12A / FN14 (TNFRSF12A 产品)
- 别名
- CD266 antibody, FN14 antibody, TWEAKR antibody, AI255180 antibody, C87282 antibody, Fn14 antibody, HPIP antibody, TWEAK-R antibody, TweakR antibody, TNF receptor superfamily member 12A antibody, tumor necrosis factor receptor superfamily, member 12a antibody, TNFRSF12A antibody, Tnfrsf12a antibody
- 背景
-
Name/Gene ID: TNFRSF12A
Synonyms: TNFRSF12A, CD266 antigen, CD266, FGF-inducible 14, FN14, Tweak-receptor, TWEAKR - 基因ID
- 51330
- 途径
- Apoptosis, Regulation of Cell Size
-