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COL2A1 抗体 (Chain alpha 1)

COL2A1 适用: 人 WB, IF, IHC (fro), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN181162
发货至: 中国
  • 抗原 See all COL2A1 抗体
    COL2A1 (Collagen, Type II, alpha 1 (COL2A1))
    抗原表位
    • 15
    • 14
    • 10
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Chain alpha 1
    适用
    • 63
    • 32
    • 30
    • 19
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 67
    • 9
    • 2
    山羊
    克隆类型
    • 70
    • 8
    多克隆
    标记
    • 45
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COL2A1 antibody is un-conjugated
    应用范围
    • 62
    • 33
    • 22
    • 14
    • 13
    • 13
    • 13
    • 12
    • 9
    • 8
    • 7
    • 5
    • 3
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Collagen II.
    纯化方法
    Purified
    Top Product
    Discover our top product COL2A1 Primary Antibody
  • 应用备注
    ELISA. Immunoblotting. Immunofluorescence. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.4 mg/mL
    缓冲液
    Borate buffered saline
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    COL2A1 (Collagen, Type II, alpha 1 (COL2A1))
    Abstract
    COL2A1 产品
    别名
    ANFH antibody, AOM antibody, COL11A3 antibody, SEDC antibody, Col2 antibody, Col2a antibody, Col2a-1 antibody, Del1 antibody, Dmm antibody, Lpk antibody, M100856 antibody, Rgsc856 antibody, CG2A1A antibody, COLLII antibody, col2a1a antibody, CB11 antibody, col2a1 antibody, coll2a1 antibody, fb38c06 antibody, fc10c01 antibody, wu:fb38c06 antibody, wu:fc10c01 antibody, collagen type II alpha 1 chain antibody, collagen, type II, alpha 1 antibody, collagen, type II, alpha 1 L homeolog antibody, collagen, type II, alpha 1 S homeolog antibody, collagen, type II, alpha 1a antibody, COL2A1 antibody, Col2a1 antibody, col2a1 antibody, col2a1.L antibody, col2a1.S antibody, col2a1a antibody
    背景
    Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON DENATURED three dimensional epitopes. This may result in diminished reactivity of some antibodies with denatured collagen or formalin fixed, paraffin embedded tissues. Type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Collagen type II is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.Synonyms: Alpha-1 type II collagen, COL2A1
    基因ID
    1280
    NCBI登录号
    NP_001835
    UniProt
    P02458
    途径
    Sensory Perception of Sound, Growth Factor Binding
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