Abeta 38/40/42 (AA 1-16), (AA 4-8) 抗体
适用: 人, 小鼠
IHC, WB
宿主: 小鼠
Monoclonal
NT244
unconjugated
(4 references)-
- 抗原
- Abeta 38/40/42
- 抗原表位
- AA 1-16, AA 4-8
- 适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- Specific for Abeta 38, 40, 42.
- 纯化方法
- purified IgG. Azide was added before lyophilization.
- 免疫原
- Synthetic peptide (aa 1-16) of abeta peptides 38, 40, 42 coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue. Epitope aa 4-8
- 克隆位点
- NT244
- 亚型
- IgG2b
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anti-Abeta 38/40/42 (AA 1-16), (AA 4-16) antibody
适用: 人, 小鼠 IHC, WB, ELISA 宿主: 小鼠 Monoclonal NT78 unconjugated
anti-Abeta 38/40/42 (AA 1-16), (AA 4-16) antibody (Biotin)适用: 人, 小鼠 IHC, WB, ELISA 宿主: 小鼠 Monoclonal NT78 Biotin
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- 应用备注
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WB: 1 : 500 up to 1 : 1000
IP: not tested yet
ICC: not tested yet
IHC-P: 1 : 500
ELISA: not tested yet - 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
- 缓冲液
- PBS, 0.02% sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.
- 储存条件
- -20 °C
- 储存方法
- Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
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: "Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease." in: Oxidative medicine and cellular longevity, Vol. 2015, pp. 967203, (2015) (PubMed).
: "Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models." in: Journal of Alzheimer's disease : JAD, Vol. 39, Issue 4, pp. 871-81, (2014) (PubMed).
: "Oligomeric pyroglutamate amyloid-β is present in microglia and a subfraction of vessels in patients with Alzheimer's disease: implications for immunotherapy." in: Journal of Alzheimer's disease : JAD, Vol. 35, Issue 4, pp. 741-9, (2013) (PubMed).
: "Antibody 9D5 recognizes oligomeric pyroglutamate amyloid-β in a fraction of amyloid-β deposits in Alzheimer's disease without cross-reactivity with other protein aggregates." in: Journal of Alzheimer's disease : JAD, Vol. 29, Issue 2, pp. 361-71, (2012) (PubMed).
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: "Oxidative Stress during the Progression of β-Amyloid Pathology in the Neocortex of the Tg2576 Mouse Model of Alzheimer's Disease." in: Oxidative medicine and cellular longevity, Vol. 2015, pp. 967203, (2015) (PubMed).
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- 抗原
- Abeta 38/40/42
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