Abeta-pE3 抗体
适用: 人, 小鼠, 大鼠
WB, IHC, IP
宿主: 小鼠
Monoclonal
1-57
unconjugated
1 image
(2 references)-
- 抗原
- Abeta-pE3
- 适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
- 应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 特异性
- Specific for Abeta-pE3.
- 纯化方法
- purified IgG. Azide was added before lyophilization.
- 免疫原
- Synthetic peptide pyr-EFRHD coupled to key-hole limpet hemocyanin via an added C-terminal cysteine residue. Epitope Minimal epitope: pyr-EFR.
- 克隆位点
- 1-57
- 亚型
- IgG2b
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anti-Abeta-pE3 antibody
适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Abeta-pE3 antibody适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 小鼠 Monoclonal 70D7 unconjugated
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- 应用备注
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WB: 1 : 1000
ICC: not tested yet
IHC: 1 : 100 - 说明
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WB: Detects purified Abeta pE3. Complex samples like brain extracts still have to be tested.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- For reconstitution add 100 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
- 缓冲液
- PBS, 0.02% sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not store diluted antibody solutions unless you add detergent or carrier proteins such as goat serum, BSA or others. IgG sticks to glass and plastic. Any IgG solution below 0.1 mg/mL protein will quickly adsorb and denature and thus loose activity! Repetitive freeze-thawing of dilute purified IgG is almost certain to lead to substantial losses.
- 储存条件
- -20 °C
- 储存方法
- Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
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: "N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody." in: Acta neuropathologica communications, Vol. 1, Issue 1, pp. 56, (2013) (PubMed).
: "Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease." in: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 8154-62, (2012) (PubMed).
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: "N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody." in: Acta neuropathologica communications, Vol. 1, Issue 1, pp. 56, (2013) (PubMed).
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- 抗原
- Abeta-pE3
- 背景
- Synonyms: pyro-Glu Abeta, pE-Abeta, pGlu-Abeta, Abeta(3(pE)-40/42)
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