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ARC (AA 2-18) 抗体

适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1731926
发货至: 中国
  • 抗原
    ARC
    抗原表位
    • 9
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-18
    适用
    • 31
    • 9
    • 9
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 30
    • 3
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 25
    • 16
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Reacts with the human, mouse, and rat ARC.
    纯化方法
    Purified
    免疫原
    Peptide corresponding to aa 2-18 of human ARC.
    亚型
    IgG
  • 应用备注
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    WB(2 μg/mL)

    Positive control: HeLa cells
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute in PBS or medium that is identical to that used in the assay system.
    储存条件
    -20 °C
    储存方法
    Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ARC
    别名
    activity regulated cytoskeleton associated protein antibody, Arc antibody
    背景
    A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The mRNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

    Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, ARC, NOP, FCM,
    基因ID
    8996
    UniProt
    O60936
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