ARC (N-Term) 抗体
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- 抗原
- ARC
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- ARC Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ARC antibody was raised against a 17 amino acid peptide near the amino terminus of human ARC. The immunogen is located within the first 50 amino acids of ARC.
- 亚型
- IgG
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anti-ARC (Middle Region) antibody
适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-ARC antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ARC antibody适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ARC (AA 1-396) antibody适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-ARC (AA 1-220) antibody适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ARC (AA 159-208) antibody适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ARC (AA 37-66) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ARC (AA 332-366), (C-Term) antibody适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ARC antibody can be used for detection of ARC by Western blot at 1:500 dilution. An approximately 25 kDa band can be detected.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ARC Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- ARC
- 别名
- activity regulated cytoskeleton associated protein antibody, Arc antibody
- 背景
- ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.
- 分子量
- 25 kDa
- 基因ID
- 8996
- NCBI登录号
- NP_003937
- UniProt
- O60936
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