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SQSTM1 抗体 (AA 232-356)

This anti-SQSTM1 antibody is a 小鼠 单克隆 antibody detecting SQSTM1 in WB, IHC, ELISA 和 FACS. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1724836
发货至: 中国

Quick Overview for SQSTM1 抗体 (AA 232-356) (ABIN1724836)

抗原

See all SQSTM1 抗体
SQSTM1 (Sequestosome 1 (SQSTM1))

适用

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  • 2
  • 2
  • 1
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宿主

  • 127
  • 38
  • 1
  • 1
小鼠

克隆类型

  • 115
  • 52
单克隆

标记

  • 108
  • 9
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  • 1
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  • 1
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  • 1
This SQSTM1 antibody is un-conjugated

应用范围

  • 120
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  • 45
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

5H7E2
  • 抗原表位

    • 17
    • 15
    • 11
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 232-356

    原理

    SQSTM1 Antibody

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified antibody in PBS with 0.05 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Inoue, Suzuki, Mitsuishi, Miki, Suzuki, Sugawara, Watanabe, Sakurada, Endo, Uruno, Sasano, Nakagawa, Satoh, Tanaka, Kubo, Motohashi, Yamamoto: "Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).

  • 抗原

    SQSTM1 (Sequestosome 1 (SQSTM1))

    别名

    SQSTM1

    背景

    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

    分子量

    47.7 kDa

    基因ID

    8878

    UniProt

    Q13501

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
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