FGFR3 抗体 (pTyr724) (Biotin)
Quick Overview for FGFR3 抗体 (pTyr724) (Biotin) (ABIN1701081)
抗原
See all FGFR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr724
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724
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亚型
- IgG
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应用备注
- ELISA 1:500-1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
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别名
- FGFR3
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背景
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Synonyms: FGFR3 phospho Y724, FGFR3 phospho Tyr724, p-FGFR3 phospho Y724, ACH, CD 333, CD333, CD333 antigen, CEK 2, CEK2, FGFR 3, Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism, Fibroblast growth factor receptor 3, Heparin binding growth factor receptor, HSFGFR3EX, Hydroxyaryl protein kinase, JTK 4, JTK4, MFR 3, SAM 3, Tyrosine kinase JTK 4, Tyrosine kinase JTK4, Z FGFR 3.
Background: The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
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基因ID
- 2261
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UniProt
- P22607
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
抗原
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