APOBEC3C 抗体 (AA 121-190) (Biotin)
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- 抗原 See all APOBEC3C 抗体
- APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))
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抗原表位
- AA 121-190
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APOBEC3C antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human APOBEC3C
- 亚型
- IgG
- Top Product
- Discover our top product APOBEC3C Primary Antibody
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anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (Center) antibody
APOBEC3C 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) antibodyAPOBEC3C 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 91-190) antibodyAPOBEC3C 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (C-Term) antibodyVerified APOBEC3C 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 1-190) antibodyAPOBEC3C 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) (AA 143-177) antibodyAPOBEC3C 适用: 人 WB 宿主: 兔 Polyclonal RB56223 unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C) antibodyAPOBEC3C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))
- 别名
- APOBEC3C (APOBEC3C 产品)
- 别名
- APOBEC3C antibody, A3C antibody, APOBEC1L antibody, ARDC2 antibody, ARDC4 antibody, ARP5 antibody, PBI antibody, bK150C2.3 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3C antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C antibody, APOBEC3C antibody
- 背景
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Synonyms: ABC3C_HUMAN, APOBEC1 like, APOBEC1-like, APOBEC1L, APOBEC3C, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C, ARDC2, ARDC4, ARP5, bK150C2.3, MGC19485, PBI, Phorbolin I, Phorbolin I protein, Probable DNA dC dU editing enzyme APOBEC 3C, Probable DNA dC->dU-editing enzyme APOBEC-3C.
Background: APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. Like APOBEC3G, APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, resulting in G to A hypermutation in the plus strand of DNA. Thus, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, and are also likely contribute to sequence variation observed in many viruses. Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome. Interestingly, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication. This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention.
- 基因ID
- 27350
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