FGF1 抗体
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- 抗原 See all FGF1 抗体
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FGF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 纯化方法
- Purified
- 过滤
- Sterile filtered
- 免疫原
- Polyclonal acidic FGF antibody was produced from sera of rabbits immunized with synthetic protein containing aFGF antigenic determinants.
- 亚型
- IgG
- Top Product
- Discover our top product FGF1 Primary Antibody
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anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibody
FGF1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibodyFGF1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) antibodyFGF1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 5-30) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-80) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 12-151) antibodyFGF1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 2-155) antibodyFGF1 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: Use at a concentration range of 1-2 µg/mL.
Western blot: A suitable range of concentrations of this antibody for WB detection is 10 µg/mL.
IHC: A suitable range of concentrations of this antibody for IHC is 10 µg/mL. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers
- 缓冲液
- PBS solution at a concentration of 1 mg/mL.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Recombinant CD48, as supplied, can be stored in working aliquots at - 8 °C for one month, or at -20 °C to -70 °C for twelve months.
- 有效期
- 12 months
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- 抗原
- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
- 别名
- aFGF (FGF1 产品)
- 别名
- AFGF antibody, ECGF antibody, ECGF-beta antibody, ECGFA antibody, ECGFB antibody, FGF-1 antibody, FGF-alpha antibody, FGFA antibody, GLIO703 antibody, HBGF-1 antibody, HBGF1 antibody, Fgf1 antibody, FGF1 antibody, aFGF antibody, ecgf antibody, fgfa antibody, ecgfa antibody, ecgfb antibody, fgf-1 antibody, hbgf1 antibody, glio703 antibody, ecgf-beta antibody, fgf-alpha antibody, Dffrx antibody, Fam antibody, Fgf-1 antibody, Fgfa antibody, zgc:136885 antibody, LOC100221393 antibody, fgf1 antibody, zgc:73249 antibody, fibroblast growth factor 1 antibody, fibroblast growth factor 1 L homeolog antibody, fibroblast growth factor 1b antibody, fibroblast growth factor 1a antibody, FGF1 antibody, fgf1.L antibody, fgf1 antibody, Fgf1 antibody, fgf1b antibody, LOC100221393 antibody, fgf1a antibody
- 背景
- CD48 is a glycosylphosphatidylinositol-anchored protein belonging to the CD2 subfamily. It is expressed mainly on hematopoietic cells and exists in both membrane-associated and soluble forms. It is a low-affinity ligand for CD2 and is implicated as an important costimulatory molecule in lymphocyte activation. Indeed, CD48 has been described as facilitating cell adhesion, innate responses to bacterial infection, and graft rejection. In addition, CD48 is a high-affinity ligand for B4. CD48/2B4 interactions can modulate T cell, B cell, and natural killer (NK) cell functions and cross-talk. The absence of functional B4/CD48 interactions impairs NK cell cytotoxic response and IFN- release on tumor target exposure. Furthermore, activated NK cells significantly increase the CD3-dependent proliferation of CD8+ and CD4+ T cells by aB4/CD48-dependent mechanism.
- UniProt
- P05230
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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