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TRAF1 抗体 (AA 217-416)

This anti-TRAF1 antibody is a 兔 多克隆 antibody detecting TRAF1 in WB. Suitable for 人.
产品编号 ABIN1683118
发货至: 中国

Quick Overview for TRAF1 抗体 (AA 217-416) (ABIN1683118)

抗原

See all TRAF1 抗体
TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TRAF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 217-416

    序列

    TSIHQSQLDR ERILSLEQRV VELQQTLAQK DQALGKLEQS LRLMEEASFD GTFLWKITNV TRRCHESACG RTVSLFSPAF YTAKYGYKLC LRLYLNGDGT GKRTHLSLFI VIMRGEYDAL LPWPFRNKVT FMLLDQNNRE HAIDAFRPDL SSASFQRPQS ETNVASGCPL FFPLSKLQSP KHAYVKDDTM FLKCIVETST

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 217-416 of human TRAF1 (NP_005649.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

    别名

    TRAF1

    背景

    The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.,TRAF1,EBI6,MGC:10353,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Growth factor,TNF,TRAF1

    分子量

    33 kDa/46 kDa

    基因ID

    7185

    UniProt

    Q13077

    途径

    NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
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