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PUMA 抗体

BBC3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7101572
发货至: 中国
  • 抗原 See all PUMA (BBC3) 抗体
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    适用
    • 96
    • 40
    • 39
    • 16
    宿主
    • 92
    • 7
    • 1
    克隆类型
    • 82
    • 18
    单克隆
    标记
    • 52
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PUMA antibody is un-conjugated
    应用范围
    • 81
    • 34
    • 30
    • 22
    • 17
    • 14
    • 14
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human PUMA
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    别名
    BBC3 (BBC3 产品)
    别名
    BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
    背景
    This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011],JFY-1, JFY1, PUMA,Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neurodegenerative Diseases,Neuroscience,BBC3
    分子量
    18 kDa
    基因ID
    27113
    UniProt
    Q96PG8, Q9BXH1
    途径
    p53 Pathway, Positive Regulation of Endopeptidase Activity
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