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HDAC4 抗体 (Internal Region)

HDAC4 适用: 人, 小鼠, 大鼠, 灵长类 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1607887
发货至: 中国
  • 抗原 See all HDAC4 抗体
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    抗原表位
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 111
    • 48
    • 34
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 灵长类
    宿主
    • 99
    • 13
    • 1
    克隆类型
    • 100
    • 13
    多克隆
    标记
    • 69
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HDAC4 antibody is un-conjugated
    应用范围
    • 85
    • 50
    • 28
    • 15
    • 13
    • 13
    • 12
    • 8
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    交叉反应 (详细)
    Cross reactivity with HDAC4 from other sources has not been determined.
    纯度
    Anti-HDAC4 was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards HDAC4. A BLAST analysis was used to suggest cross-reactivity with Human, Mouse, Rat, and Primate based on 100 % sequence homology.
    内毒素水平
    Low Endotoxin : No
    免疫原
    HDAC4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region of human HDAC4.
    Immunogen Type: Peptide
    Top Product
    Discover our top product HDAC4 Primary Antibody
  • 应用备注
    Anti-HDAC4 antibody is useful for ELISA, immunohistochemistry, and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~140 kDa corresponding to the appropriate cell lysate or extract.
    ELISA Dilution: 1:20.000 - 1:60.000
    Immunohistochemistry Dilution: 1 mg/mL
    IF Microscopy Dilution: 1:100-1:500
    Western Blot Dilution: 1 mg/mL
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Stabilizer: 50 % (v/v) Glycerol
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    Expiration date is six (6) months from date of opening.
  • 抗原
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    别名
    HDAC4 (HDAC4 产品)
    别名
    CG1770 antibody, DHDAC4 antibody, Dmel\\CG1770 antibody, GC1770 antibody, HDAC antibody, HDAC4a antibody, dHDAC4 antibody, dmHDA405 antibody, hdac4 antibody, dana_GLEANR_19966 antibody, DanaGF18710 antibody, GF18710 antibody, HDAC4 antibody, AHO3 antibody, BDMR antibody, HA6116 antibody, HD4 antibody, HDAC-4 antibody, HDAC-A antibody, HDACA antibody, 4932408F19Rik antibody, AI047285 antibody, wu:fa96d08 antibody, wu:fc56f08 antibody, zgc:152701 antibody, histone deacetylase 4 antibody, hypothetical protein antibody, Histone deacetylase 4 antibody, GF18710 gene product from transcript GF18710-RC antibody, PTRG_03699 antibody, PGTG_15512 antibody, HDAC4 antibody, Dana\GF18710 antibody, Hdac4 antibody, hdac4 antibody
    背景
    HDAC4 is a 140 kD class II histone deacetylase similar to the yeast HDA1 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC4 uses active nuclear export to shuttle between the nucleus and the cytoplasm. HDAC4 is modified by phosphorylation by CaM kinase I or IV. HDAC4 has been reported to interact with 14-3-3 in the cytoplasm and MEF2A, HDAC3, NcoR and SMRT in the nucleus. Anti-HDAC4 antibodies are ideal for researchers interested in Breast Cancer, Cancer, Cell Cycle and Replication, Chromatin Research, Epigenetics, and Histone Deacetylases research. Synonyms: HA6116, HDAC-A, HDACABDMR, HD4EC 3.5.1.98, histone deacetylase A, histone deacetylase 4, KIAA0288AHO3
    基因ID
    9759
    NCBI登录号
    NP_006028
    UniProt
    P56524
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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