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HDAC4 抗体 (pSer632)

HDAC4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256389
发货至: 中国
  • 抗原 See all HDAC4 抗体
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    抗原表位
    • 15
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    • 11
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    pSer632
    适用
    • 113
    • 51
    • 34
    • 6
    • 6
    • 4
    • 4
    • 4
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    • 1
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 101
    • 13
    • 1
    克隆类型
    • 102
    • 13
    多克隆
    标记
    • 71
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    This HDAC4 antibody is un-conjugated
    应用范围
    • 87
    • 50
    • 29
    • 16
    • 13
    • 13
    • 13
    • 10
    • 8
    • 4
    • 4
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-HDAC4 (Ser632) Antibody detects endogenous levels of HDAC4 only when phosphorylated at Serine 632.
    预测反应
    Pig,Zebrafish,Bovine,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human HDAC4 around the phosphorylation site of Ser632.
    亚型
    IgG
    Top Product
    Discover our top product HDAC4 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    别名
    HDAC4 (HDAC4 产品)
    别名
    CG1770 antibody, DHDAC4 antibody, Dmel\\CG1770 antibody, GC1770 antibody, HDAC antibody, HDAC4a antibody, dHDAC4 antibody, dmHDA405 antibody, hdac4 antibody, dana_GLEANR_19966 antibody, DanaGF18710 antibody, GF18710 antibody, HDAC4 antibody, AHO3 antibody, BDMR antibody, HA6116 antibody, HD4 antibody, HDAC-4 antibody, HDAC-A antibody, HDACA antibody, 4932408F19Rik antibody, AI047285 antibody, wu:fa96d08 antibody, wu:fc56f08 antibody, zgc:152701 antibody, histone deacetylase 4 antibody, hypothetical protein antibody, Histone deacetylase 4 antibody, GF18710 gene product from transcript GF18710-RC antibody, PTRG_03699 antibody, PGTG_15512 antibody, HDAC4 antibody, Dana\GF18710 antibody, Hdac4 antibody, hdac4 antibody
    背景

    Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. Deacetylates HSPA1A and HSPA1B at 'Lys-77' leading to their preferential binding to co-chaperone STUB1 (PubMed:27708256).

    Gene: HDAC4

    分子量
    119kDa
    基因ID
    9759
    UniProt
    P56524
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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