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c-FOS 抗体 (AA 250-300)

c-Fos 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1574157
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗原表位
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    AA 250-300
    适用
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    人, 大鼠
    宿主
    • 200
    • 36
    • 8
    • 1
    克隆类型
    • 197
    • 47
    多克隆
    标记
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    This c-FOS antibody is un-conjugated
    应用范围
    • 204
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    • 26
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    Western Blotting (WB)
    特异性
    Rabbit Anti-C-Fos Polyclonal Antibody detects human C-Fos protein. Predicted to react with rat C-Fos according to sequence homology.
    交叉反应 (详细)
    Rabbit Anti-C-Fos Polyclonal Antibody detects human C-Fos protein. Predicted to react with rat C-Fos according to sequence homology.
    纯化方法
    Immunoaffinity chromatography.
    免疫原
    KLH-coupled synthetic peptide within AA 250~300 of human C-Fos .
    亚型
    IgG2b
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

    Western blot: 0.5-1 µg/mL
    Other Applications: user-optimized
    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4, containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C/-20 °C
    储存方法
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    C-Fos (c-Fos 产品)
    别名
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    背景
    Transcription factor C-Fos is one member of Fos family of nuclear oncogenes which includes c-Fos, FosB, Fos-related antigen 1 (FRA1) and Fos-related antigen 2 (FRA2).C-Fos is a major component of the activator protein-1 (AP-1) transcription factor complex and dimerizes with Jun proteins (c-Jun, JunB and JunD) to form AP-1 complex. AP-1 upregulates transcription of a diverse range of genes containing AP-1 regulatory elements. And phosphorylation of c-Fos on serine 32 and threonine 232 by ERK-5 increases protein stability and nuclear localization. C-Fos probably serves as a genetic regulator for cellular mechanisms mediating neuronal excitability and survival vial regulation of kainic acid receptor GLUR6 and expression of brain-derived neurotrophic factor BDNF.Rabbit Anti-C-Fos Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 250~300 of human C-Fos (Swiss Prot: P01100).
    途径
    S100 Proteins
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