(1 reference)-
- 抗原 See all Fibrillarin (FBL) 抗体
- Fibrillarin (FBL)
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抗原表位
- AA 50-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Fibrillarin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Rabbit Anti-Fibrillarin Polyclonal Antibody detects endogenous levels of human Fibrillarin.Positive Control: Hela and HEK293.
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- KLH-coupled synthetic peptide within AA 50-100 of human Fibrillarin protein .
- 亚型
- IgG
- Top Product
- Discover our top product FBL Primary Antibody
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anti-Fibrillarin (FBL) (AA 100-321) antibody
FBL 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: Saccharomyces cerevisiae WB, IF 宿主: 小鼠 Monoclonal 38F3 unconjugated
anti-Fibrillarin (FBL) (AA 1-321) antibodyFBL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G9-E4 unconjugated
anti-Fibrillarin (FBL) antibodyFBL 适用: Saccharomyces cerevisiae WB, IF, ICC, IHC (p) 宿主: 小鼠 Monoclonal 38F3 unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (Internal Region) antibodyFBL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (AA 61-110) antibodyFBL 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mLOther Applications: user-optimized - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
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: "The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background." in: Developmental biology, Vol. 360, Issue 2, pp. 358-68, (2011) (PubMed).
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: "The first bromodomain of the testis-specific double bromodomain protein Brdt is required for chromocenter organization that is modulated by genetic background." in: Developmental biology, Vol. 360, Issue 2, pp. 358-68, (2011) (PubMed).
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- 抗原
- Fibrillarin (FBL)
- 别名
- Fibrillarin (FBL 产品)
- 别名
- FIB antibody, FLRN antibody, RNU3IP1 antibody, wu:fb37g12 antibody, zgc:56145 antibody, zgc:77130 antibody, FBL antibody, AL022665 antibody, CG9888 antibody, Dmel\\CG9888 antibody, Fibri antibody, GCR-6 antibody, GCR6 antibody, Pen59C5 antibody, fib antibody, pen59C5 antibody, MGC76139 antibody, fbl antibody, fibrillarin antibody, Fibrillarin antibody, putative fibrillarin antibody, fibrillarin S homeolog antibody, FBL antibody, fbl antibody, Fbl antibody, Fib antibody, fib1 antibody, LMJF_19_0100 antibody, fbl.S antibody
- 背景
- Fibrillarin is an excellent marker for the nucleolus. As a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle, it is thought to participate in the first step in processing preribosomal RNA. Fibrillarin protein contains an amino-terminal domain that is rich in glycine and arginine residues (termed the GAR domain), a central RNA-binding domain comprising an RNP-2 like consensus sequence, and a C-terminal alpha-helical domain. Fibrillarin binds to U3, U8, and U13 small nuclear RNAs. It associates with several other structural proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. Rabbit Anti-Fibrillarin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 50-100 of human Fibrillarin protein (Swiss Prot: P22087).
- 途径
- Ribonucleoside Biosynthetic Process
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