我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Fibrillarin 抗体 (N-Term)

There are 2+ publications for this product available. The 兔多克隆 anti-Fibrillarin antibody is suitable to detect Fibrillarin in samples from 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马和兔. It has been validated for WB 和 IHC.

Rabbit Anti-FBL Antibody Paraffin Embedded Tissue: Human Intestine Cellular Data: Epithelial cells of intestinal villas Antibody Concentration: 4. (Fibrillarin 抗体 (N-Term))

IHC

3 images

(2 references)

产品编号 ABIN2778775

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Fibrillarin 抗体 (N-Term) (ABIN2778775)

抗原

See all Fibrillarin (FBL) 抗体

Fibrillarin (FBL)

适用

人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔

宿主

兔

克隆类型

多克隆

标记

This Fibrillarin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product FBL Primary Antibody

抗原表位
13

3

3

2

1

1

1

1

1

1

1

1

1

1

1
N-Term

原理

FBL Antibody - N-terminal region

序列

GGGFHSGGNR GRGRGGKRGN QSGKNVMVEP HRHEGVFICR GKEDALVTKN

预测反应

Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against FBL. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human FBL
anti-Fibrillarin (FBL) antibody
FBL 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (AA 100-321) antibody
FBL 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: Saccharomyces cerevisiae WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 38F3 unconjugated

anti-Fibrillarin (FBL) antibody
FBL 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5735 unconjugated Recombinant Antibody

anti-Fibrillarin (FBL) (AA 1-321) antibody
FBL 适用: 人 IF, ELISA 宿主: 小鼠 Monoclonal 4G9-E4 unconjugated

anti-Fibrillarin (FBL) (AA 61-110) antibody
FBL 适用: 人, 大鼠, 小鼠, 猴, 犬, Cow, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (N-Term) antibody
FBL 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fibrillarin (FBL) (Internal Region) antibody
FBL 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

说明

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100617

限制

仅限研究用
状态

Liquid

浓度

1.0 mg/mL

缓冲液

Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

prevent freeze-thaw cycles

储存条件

4 °C,-20 °C

储存方法

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Ernoult-Lange, Wilczynska, Harper, Aigueperse, Dautry, Kress, Weil: "Nucleocytoplasmic traffic of CPEB1 and accumulation in Crm1 nucleolar bodies." in: Molecular biology of the cell, Vol. 20, Issue 1, pp. 176-87, (2009) (PubMed).

Armistead, Khatkar, Meyer, Mark, Patel, Coghlan, Lamont, Liu, Wiechert, Cattini, Koetter, Wrogemann, Greenberg, Entian, Zelinski, Triggs-Raine: "Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome." in: American journal of human genetics, Vol. 84, Issue 6, pp. 728-39, (2009) (PubMed).
抗原

Fibrillarin (FBL)

别名

FBL

背景

Background Information: FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
Gene Name: Fibrillarin
Alternative Symbols: FIB, FLRN, Nop1, RNU3IP1
Protein Name: rRNA 2'-O-methyltransferase fibrillarin

分子量

35kDa

基因ID

2091

NCBI登录号

NP_001427

UniProt

P22087

途径

Ribonucleoside Biosynthetic Process