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- 抗原 See all WISP2 抗体
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- 适用
- 请咨询
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This WISP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Protein A affinity column
- 免疫原
- WISP2 full length recombinant protein with GST tag
- 克隆位点
- 5D11E11
- 亚型
- IgG
- Top Product
- Discover our top product WISP2 Primary Antibody
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anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 1-250) antibody
WISP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-250) antibodyWISP2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 1-250) antibodyWISP2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 1-250) antibodyWISP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) antibodyWISP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-250) antibodyWISP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) antibodyWISP2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 151-250) antibodyWISP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 87-116) antibodyWISP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2114 unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) (AA 24-250) antibodyWISP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA: 0.05-0.2 µg/mL
Western blot: 0.1-1.0 µg/mL
Other applications: user-optimized - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
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- 抗原
- WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))
- 别名
- WISP2 (WISP2 产品)
- 别名
- MGC84196 antibody, WISP2 antibody, ccn5 antibody, CCN5 antibody, CT58 antibody, CTGF-L antibody, Ccn5 antibody, Crgr4 antibody, Ctgfl antibody, Rcop1 antibody, WNT1 inducible signaling pathway protein 2 antibody, WNT1 inducible signaling pathway protein 2 S homeolog antibody, WISP2 antibody, wisp2.S antibody, wisp2 antibody, Wisp2 antibody
- 背景
- WISP-2 is a member of the connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (nov) (CCN) family and is upregulated in the mouse mammary epithelial cell line C57MG transformed by Wnt-1 and in several non-invasive human breast tumor cell lines. WISP-2 expression is enhanced by important modulators of human breast cancer cell proliferation such as estrogen, progesterone and epidermal growth factor (EGF) in MCF-7 cells. These effects, inhibited by appropriate antagonists, indicate that steroids and growth factor-induced upregulation of WISP-2 may be mediated through receptors. WISP2 gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
- 途径
- WNT signaling, Growth Factor Binding
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