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Insulin 抗体 (AA 35-64)

This 小鼠 单克隆 anti-Insulin antibody (Clone 396CT20-4-4) specifically detects Insulin in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1539839
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Insulin 抗体 (AA 35-64) (ABIN1539839)

抗原

See all Insulin (INS) 抗体
Insulin (INS)

适用

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宿主

  • 168
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小鼠

克隆类型

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  • 1
单克隆

标记

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This Insulin antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

396CT20-4-4
  • 抗原表位

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    AA 35-64

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This INS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from human INS.

    亚型

    IgM
  • 应用备注

    WB: 1:1000~8000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    INS Antibody (Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    Insulin (INS)

    别名

    INS

    背景

    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

    分子量

    11981

    基因ID

    3630

    NCBI登录号

    NP_000198, NP_001172026, NP_001172027

    UniProt

    P01308

    途径

    NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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