This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ULK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-564 amino acids from the Central region of human ULK1.
ULK1 is involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).