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Lamin A/C 抗体 (AA 401-427)

The 兔多克隆 anti-Lamin A/C antibody is suitable to detect Lamin A/C in samples from 人. It has been validated for WB.

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产品编号 ABIN1538393

发货至: 中国

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Quick Overview for Lamin A/C 抗体 (AA 401-427) (ABIN1538393)

抗原

See all Lamin A/C (LMNA) 抗体

Lamin A/C (LMNA)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Lamin A/C antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB21443

Discover our top product LMNA Primary Antibody

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AA 401-427

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This LMNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-427 amino acids from the Central region of human LMNA.

亚型

Ig Fraction
anti-Lamin A/C (LMNA) (AA 403-572) antibody
LMNA 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
KO Validated LMNA 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (pSer392) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人 IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 4H7 unconjugated Recombinant Antibody

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Lamin A/C (LMNA) (AA 481-646) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (AA 455-469) antibody
LMNA 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lamin A/C (LMNA) (C-Term) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 猴, 兔, 马, 小鸡, Hamster, 绵羊, 豚鼠, Avian, Cat, 驴, 山羊 WB 宿主: 山羊 Polyclonal unconjugated

anti-Lamin A/C (LMNA) antibody
LMNA 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 133A2 unconjugated

anti-Lamin A/C (LMNA) (AA 1-664) antibody
LMNA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

LMNA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

有效期

6 months
抗原

Lamin A/C (LMNA)

别名

LMNA

背景

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

分子量

74139

基因ID

4000

NCBI登录号

NP_001244303, NP_005563, NP_733821, NP_733822

UniProt

P02545

途径

Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus