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Lamin A/C 抗体 (AA 401-427)

This anti-Lamin A/C antibody is a 兔 多克隆 antibody detecting Lamin A/C in WB. Suitable for 人.
产品编号 ABIN1538393
发货至: 中国

Quick Overview for Lamin A/C 抗体 (AA 401-427) (ABIN1538393)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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宿主

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克隆类型

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多克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB21443
  • 抗原表位

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    AA 401-427

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LMNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-427 amino acids from the Central region of human LMNA.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    LMNA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    Lamin A/C (LMNA)

    别名

    LMNA

    背景

    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

    分子量

    74139

    基因ID

    4000

    NCBI登录号

    NP_001244303, NP_005563, NP_733821, NP_733822

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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