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JNK2 抗体 (AA 246-295)

The 兔 多克隆 anti-JNK2 antibody is suitable to detect JNK2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1534420
发货至: 中国
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Quick Overview for JNK2 抗体 (AA 246-295) (ABIN1534420)

抗原

See all JNK2 (MAPK9) 抗体
JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

适用

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人, 小鼠, 大鼠

宿主

  • 75
  • 8
  • 3
  • 2
兔

克隆类型

  • 63
  • 27
多克隆

标记

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This JNK2 antibody is un-conjugated

应用范围

  • 67
  • 40
  • 31
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  • 17
  • 9
  • 1
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 12
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 246-295

    原理

    JNK2 Antibody

    特异性

    JNK2 Polyclonal Antibody detects endogenous levels of JNK2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MAPK9. AA range:246-295

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))

    别名

    MAPK9

    背景

    Synonyms: MAPK9; JNK2; PRKM9; SAPK1A; Mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2

    Background: The protein encoded byThis gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternative

    Gene Name: MAPK9

    Protein Name: Mitogen-activated protein kinase 9

    分子量

    48 kDa

    基因ID

    5601

    OMIM

    602896

    UniProt

    P45984

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins
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