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JNK2 抗体

MAPK9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7244543
发货至: 中国
  • 抗原 See all JNK2 (MAPK9) 抗体
    JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
    适用
    • 74
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    人, 小鼠, 大鼠
    宿主
    • 59
    • 8
    • 3
    • 2
    • 1
    克隆类型
    • 57
    • 18
    多克隆
    标记
    • 44
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    This JNK2 antibody is un-conjugated
    应用范围
    • 52
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    • 5
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    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human MAPK9
    亚型
    IgG
    Top Product
    Discover our top product MAPK9 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
    别名
    JNK2 (MAPK9 产品)
    别名
    MAPK9 antibody, JNK-55 antibody, JNK2 antibody, JNK2A antibody, JNK2ALPHA antibody, JNK2B antibody, JNK2BETA antibody, PRKM9 antibody, SAPK antibody, SAPK1a antibody, p54a antibody, p54aSAPK antibody, AI851083 antibody, Prkm9 antibody, JNK2-ALPHA1 antibody, MAP kinase 9 antibody, mitogen-activated protein kinase 9 antibody, MAP kinase 9 antibody, MAPK9 antibody, Mapk9 antibody, MPK9 antibody
    背景
    Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 48 kDa

    NCBI登录号
    NP_620707
    UniProt
    P45984
    途径
    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteins
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