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Lamin A/C 抗体 (pSer22)

This anti-Lamin A/C antibody is a 兔 多克隆 antibody detecting Lamin A/C in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1532183
发货至: 中国

Quick Overview for Lamin A/C 抗体 (pSer22) (ABIN1532183)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠, 大鼠

宿主

  • 111
  • 48
  • 2
  • 1

克隆类型

  • 109
  • 53
多克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 2-51, pSer22

    特异性

    Lamin A (Phospho-Ser22) Antibody detects endogenous levels of Lamin A only when phosphorylated at Ser22.

    PhosphorylationH:S22 M:S22 R:S22

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Lamin A around the phosphorylation site of Ser22.

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:1000 ELISA: 1:1000

    说明

    Unigene-Number: Hs.594444 (NCBI Gene Symbol: LMNA)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • Häge, Sonntag, Svrlanska, Borst, Stilp, Horsch, Müller, Kropff, Milbradt, Stamminger, Schlötzer-Schrehardt, Marschall: "Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation." in: Viruses, Vol. 13, Issue 2, (2021) (PubMed).

    Schütz, Steingruber, Socher, Müller, Wagner, Kögel, Sticht, Marschall: "Functional Relevance of the Interaction between Human Cyclins and the Cytomegalovirus-Encoded CDK-Like Protein Kinase pUL97." in: Viruses, Vol. 13, Issue 7, (2021) (PubMed).

    Häge, Büscher, Pakulska, Hahn, Adrait, Krauter, Borst, Schlötzer-Schrehardt, Couté, Plachter, Marschall: "The Complex Regulatory Role of Cytomegalovirus Nuclear Egress Protein pUL50 in the Production of Infectious Virus." in: Cells, Vol. 10, Issue 11, (2021) (PubMed).

  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A

    背景

    Synonyms: 70 kDa lamin, LAMA, LMN1, LMNA

    NCBI Gene Symbol: LMNA

    分子量

    74 kDa

    基因ID

    4000

    OMIM

    115200

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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