EPH Receptor A3 抗体 (pTyr779, pTyr833)
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Quick Overview for EPH Receptor A3 抗体 (pTyr779, pTyr833) (ABIN1532042)
抗原
See all EPH Receptor A3 (EPHA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 746-795, pTyr779, pTyr833
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原理
- EphA3/4/5 (phospho Tyr779/833) Antibody
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特异性
- Phospho-EphA3/4/5 (Y779/833) Polyclonal Antibody detects endogenous levels of EphA3/4/5 protein only when phosphorylated at Y779/833.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human EPHA3/4/5 around the phosphorylation site of Tyr779/833. AA range:746-795
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- EPH Receptor A3 (EPHA3)
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别名
- EPHA3/4/5
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背景
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Synonyms: EPHA3, ETK, ETK1, HEK, TYRO4, Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1, EPHA4, HEK8, SEK, TYRO1, Ephri
Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: EPHA3/EPHA4/EPHA5
Protein Name: Ephrin type-A receptor 3/4/5
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分子量
- 110 kDa
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基因ID
- 2042, 2043, 54764
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OMIM
- 114500
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UniProt
- P29320
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途径
- RTK signaling, Regulation of Cell Size
抗原
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