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EPH Receptor A3 抗体 (C-Term)

EPHA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261558
发货至: 中国
  • 抗原 See all EPH Receptor A3 (EPHA3) 抗体
    EPH Receptor A3 (EPHA3)
    抗原表位
    • 19
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    C-Term
    适用
    • 80
    • 58
    • 50
    • 9
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    人, 小鼠, 大鼠
    宿主
    • 90
    • 5
    • 1
    克隆类型
    • 90
    • 6
    多克隆
    标记
    • 39
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    This EPH Receptor A3 antibody is un-conjugated
    应用范围
    • 61
    • 34
    • 21
    • 13
    • 13
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    EPHA3 Antibody detects endogenous levels of total EPHA3.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EPHA3, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product EPHA3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    EPH Receptor A3 (EPHA3)
    别名
    EPHA3 (EPHA3 产品)
    别名
    EK4 antibody, ETK antibody, ETK1 antibody, HEK antibody, HEK4 antibody, TYRO4 antibody, EPHA3 antibody, AW492086 antibody, Cek4 antibody, End3 antibody, Hek antibody, Hek4 antibody, Mek4 antibody, Tyro4 antibody, CEK4 antibody, EPH receptor A3 antibody, ephrin type-A receptor 3 antibody, Eph receptor A3 antibody, EPHA3 antibody, LOC100439679 antibody, Epha3 antibody
    背景

    Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

    Gene: EPHA3

    分子量
    110 kDa
    基因ID
    2042
    UniProt
    P29320
    途径
    RTK signaling, Regulation of Cell Size
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