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Caspase 8 抗体 (pTyr380)

This anti-Caspase 8 antibody is a 兔 多克隆 antibody detecting Caspase 8 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1532005
发货至: 中国

Quick Overview for Caspase 8 抗体 (pTyr380) (ABIN1532005)

抗原

See all Caspase 8 (CASP8) 抗体
Caspase 8 (CASP8)

适用

  • 139
  • 69
  • 62
  • 23
  • 16
  • 16
  • 11
  • 1
  • 1

宿主

  • 133
  • 27
  • 5
  • 2

克隆类型

  • 130
  • 36
多克隆

标记

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  • 1
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This Caspase 8 antibody is un-conjugated

应用范围

  • 149
  • 55
  • 46
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  • 20
  • 8
  • 4
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Western Blotting (WB), ELISA
  • 抗原表位

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    • 2
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
    AA 346-395, pTyr380

    特异性

    Caspase 8 (Phospho-Tyr380) Antibody detects endogenous levels of Caspase 8 only when phosphorylated at Tyr380.

    PhosphorylationH:Y380

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Tyr380.

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:1000 ELISA: 1:10000

    说明

    Unigene-Number: Hs.599762 (NCBI Gene Symbol: CASP8)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • Xu, Xu, Zhou, Zhuang, Wang, Boerner, Wu: "Regulation of the Src-PP2A interaction in tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33263-71, (2013) (PubMed).

  • 抗原

    Caspase 8 (CASP8)

    别名

    Caspase 8

    背景

    Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, Caspase-8 precursor, FADD-homologous ICE/CED-3- like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, ICE8, MACH, MCH5, MORT1-associated CED-3 homolog

    NCBI Gene Symbol: CASP8

    分子量

    55 kDa

    基因ID

    841

    OMIM

    211980

    UniProt

    Q14790

    途径

    Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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