ATF2 抗体 (pSer480)
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北京 101111
Quick Overview for ATF2 抗体 (pSer480) (ABIN1531522)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 456-505, pSer480
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原理
- ATF-2 (phospho Ser480) Antibody
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特异性
- Phospho-ATF-2 (S480) Polyclonal Antibody detects endogenous levels of ATF-2 protein only when phosphorylated at S480.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human ATF2 around the phosphorylation site of Ser480. AA range:456-505
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亚型
- IgG
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anti-Activating Transcription Factor 2 (ATF2) (AA 1-190) antibody
ATF2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 93-450) antibodyATF2 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) antibodyATF2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4F12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (pThr73) antibodyATF2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 1-209) antibodyATF2 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 91-190) antibodyATF2 适用: 人 IF, PLA 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Activating Transcription Factor 2 (ATF2) antibodyATF2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Activating Transcription Factor 2 (ATF2) (C-Term) antibodyATF2 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (pThr51), (pThr53) antibodyATF2 适用: 小鼠 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 2 (ATF2) (AA 401-450) antibodyATF2 适用: 人, 小鼠, 大鼠, 小鸡, 猴, Cow, 兔, 马, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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别名
- ATF2
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背景
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Synonyms: ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro
Background: activating transcription factor 2(ATF2) Homo sapiens This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014
Gene Name: ATF2
Protein Name: Cyclic AMP-dependent transcription factor ATF-2
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分子量
- 52 kDa
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基因ID
- 1386
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OMIM
- 123811
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UniProt
- P15336
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途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
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