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BAX 抗体 (pThr167)

There are 5+ publications for this product available. The 兔多克隆 anti-BAX antibody is suitable to detect BAX in samples from 人, 小鼠和大鼠. It has been validated for ELISA 和 IF.

1 image

(5 references)

产品编号 ABIN1531490

发货至: 中国

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Quick Overview for BAX 抗体 (pThr167) (ABIN1531490)

抗原

See all BAX 抗体

BAX (BCL2-Associated X Protein (BAX))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This BAX antibody is un-conjugated

应用范围

ELISA, Immunofluorescence (IF)

Discover our top product BAX Primary Antibody

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AA 133-182, pThr167

原理

Bax (phospho Thr167) Antibody

特异性

Phospho-Bax (T167) Polyclonal Antibody detects endogenous levels of Bax protein only when phosphorylated at T167.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

纯度

> 95 %

免疫原

The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167. AA range:133-182

亚型

IgG
anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX 适用: 人 WB, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibody
BAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibody
BAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated

anti-BCL2-Associated X Protein (BAX) (N-Term) antibody
BAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 犬, 绵羊, Hamster, 兔, 小鸡, 马, 豚鼠, Avian, Cat, 驴, 山羊 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibody
BAX 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 4H9B11 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
BAX 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2G6B2 unconjugated

anti-BCL2-Associated X Protein (BAX) antibody
KD Validated BAX 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB450 unconjugated Recombinant Antibody

anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibody
BAX 适用: 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibody
BAX 适用: 人 IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated

应用备注

IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C/1 year

有效期

12 months
Grossini, Marotta, Farruggio, Sigaudo, Qoqaiche, Raina, de Giuli, Mary, Vacca, Pollastro: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." in: Phytotherapy research : PTR, (2015) (PubMed).

Grossini, Bellofatto, Farruggio, Sigaudo, Marotta, Raina, De Giuli, Mary, Pollesello, Minisini, Pirisi, Vacca: "Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124742, (2015) (PubMed).

Grossini, Gramaglia, Farruggio, Bellofatto, Anchisi, Mary, Vacca, Zeppegno: "Asenapine increases nitric oxide release and protects porcine coronary artery endothelial cells against peroxidation." in: Vascular pharmacology, Vol. 60, Issue 3, pp. 127-41, (2014) (PubMed).

Grossini, Pollesello, Bellofatto, Sigaudo, Farruggio, Origlia, Mombello, Mary, Valente, Vacca: "Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats." in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 20, Issue 3, pp. 361-75, (2014) (PubMed).

Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).
抗原

BAX (BCL2-Associated X Protein (BAX))

别名

Bax

背景

Synonyms: BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
Background: The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.
Gene Name: BAX
Protein Name: Apoptosis regulator BAX

分子量

21 kDa

基因ID

581

OMIM

600040

UniProt

Q07812

途径

p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response