p53 抗体 (pSer392)
Quick Overview for p53 抗体 (pSer392) (ABIN1531357)
抗原
See all p53 (TP53) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 344-393, pSer392
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特异性
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p53 (Phospho-Ser392) Antibody detects endogenous levels of p53 only when phosphorylated at Ser392.
PhosphorylationH:S392
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human p53 around the phosphorylation site of Ser392.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000
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说明
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Unigene-Number: Hs.654481 (NCBI Gene Symbol: TP53)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- p53 (TP53) (Tumor Protein P53 (TP53))
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别名
- p53
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背景
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Synonyms: Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53
NCBI Gene Symbol: TP53
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分子量
- 43 kDa
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基因ID
- 7157
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OMIM
- 133239
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UniProt
- P04637
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途径
- p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
抗原
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