PKC zeta 抗体 (pThr410)
Our Local Distributor
北京 101111
Quick Overview for PKC zeta 抗体 (pThr410) (ABIN1531192)
抗原
See all PKC zeta (PRKCZ) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 376-425, pThr410
-
原理
- PKC ζ (phospho Thr410) Antibody
-
特异性
- Phospho-PKC ζ (T410) Polyclonal Antibody detects endogenous levels of PKC ζ protein only when phosphorylated at T410.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human PKC zeta around the phosphorylation site of Thr410. AA range:376-425
-
亚型
- IgG
-
-
anti-Protein Kinase C, zeta (PRKCZ) (AA 453-592) antibody
PRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 165-255) antibodyPRKCZ 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (Cytoplasmic Domain) antibodyPRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, ELISA, IP 宿主: 兔 Monoclonal R14-K unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (AA 166-197), (N-Term) antibodyPRKCZ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01027 unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (N-Term) antibodyPRKCZ 适用: 人 IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr410) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (C-Term) antibodyPRKCZ 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, zeta (PRKCZ) (pThr560) antibodyPRKCZ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB890 unconjugated Recombinant Antibody
anti-Protein Kinase C, zeta (PRKCZ) antibodyPRKCZ 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4195 unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
-
别名
- PKC zeta
-
背景
-
Synonyms: PRKCZ, PKC2, Protein kinase C zeta type, nPKC-zeta
Background: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Gene Name: PRKCZ
Protein Name: Protein kinase C zeta type
-
分子量
- 67 kDa
-
基因ID
- 5590
-
OMIM
- 176982
-
UniProt
- Q05513
-
途径
- NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
抗原
-
