Retinoblastoma 1 抗体 (AA 701-928)
(1 reference)Quick Overview for Retinoblastoma 1 抗体 (AA 701-928) (ABIN1513471)
抗原
See all Retinoblastoma 1 (RB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-928
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序列
- DQIMMCSMYG ICKVKNIDLK FKIIVTAYKD LPHAVQETFK RVLIKEEEYD SIIVFYNSVF MQRLKTNILQ YASTRPPTLS PIPHIPRSPY KFPSSPLRIP GGNIYISPLK SPYKISEGLP TPTKMTPRSR ILVSIGESFG TSEKFQKINQ MVCNSDRVLK RSAEGSNPPK PLKKLRFDIE GSDEADGSKH LPGESKFQQK LAEMTSTRTR MQKQKMNDSM DTSNKEEK
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 701-928 of human RB (NP_000312.2).
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亚型
- IgG
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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer795) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807), (pSer811) antibodyRB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (AA 639-778) antibodyRB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." in: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).
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: "Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs." in: Cell cycle (Georgetown, Tex.), Vol. 16, Issue 2, pp. 172-178, (2017) (PubMed).
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- Retinoblastoma 1 (RB1)
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别名
- RB1
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背景
- The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.,OSRC,PPP1R130,RB,p105-Rb,pRb,pp110,RB1,Rb,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,G1/S Checkpoint,RB1
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分子量
- 106 kDa
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基因ID
- 5925
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UniProt
- P06400
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途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
抗原
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