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- 抗原 See all SDHD 抗体
- SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))
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抗原表位
- Middle Region
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SDHD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 15 amino acid synthetic peptide near the center of Human SDHD
- 亚型
- IgG
- Top Product
- Discover our top product SDHD Primary Antibody
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anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 13-42) antibody
SDHD 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 13-42), (N-Term) antibodySDHD 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB31963 unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 81-159) antibodySDHD 适用: 人, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 1-159) antibodySDHD 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 20-50), (N-Term) antibodySDHD 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) antibodySDHD 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD) (AA 50-150) antibodySDHD 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))
- 别名
- SDHD (SDHD 产品)
- 别名
- RATSDHE1 antibody, SDH2 antibody, Sdh antibody, Sdhe1 antibody, TDH antibody, 3110001M13Rik antibody, AVLL5809 antibody, C78570 antibody, PRO19626 antibody, CII-4 antibody, CII4 antibody, QPs3 antibody, cybS antibody, CybS antibody, CBT1 antibody, CWS3 antibody, PGL antibody, PGL1 antibody, SDH4 antibody, MSN2.16 antibody, MSN2_16 antibody, succinate dehydrogenase 1-1 antibody, CybS-B antibody, cbt1 antibody, pgl antibody, pgl1 antibody, sdh4 antibody, cybS-B antibody, sdhd antibody, sdhda antibody, zgc:100986 antibody, serine dehydratase antibody, succinate dehydrogenase complex, subunit D, integral membrane protein antibody, succinate dehydrogenase complex subunit D antibody, succinate dehydrogenase 1-1 antibody, succinate dehydrogenase complex subunit D, integral membrane protein L homeolog antibody, succinate dehydrogenase complex, subunit D, integral membrane protein b antibody, Sds antibody, Sdhd antibody, SDHD antibody, SDH1-1 antibody, sdhd.L antibody, sdhdb antibody
- 背景
- The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.Synonyms: CII-4, CybS, QPs3, SDH4, Succinate dehydrogenase [ubiquinone] cytochrome b small subunit mitochondrial, Succinate dehydrogenase complex subunit D, Succinate-ubiquinone oxidoreductase cytochrome b small subunit, Succinate-ubiquinone reductase membrane anchor subunit
- 基因ID
- 6392
- NCBI登录号
- NP_002993
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