SDHD 抗体 (AA 50-150)
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北京 101111
Quick Overview for SDHD 抗体 (AA 50-150) (ABIN7270622)
抗原
See all SDHD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-150
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原理
- SDHD Rabbit pAb
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序列
- HLSPSHHSGS KAASLHWTSE RVVSVLLLGL LPAAYLNPCS AMDYSLAAAL TLHGHWGLGQ VVTDYVHGDA LQKAAKAGLL ALSALTFAGL CYFNYHDVGI C
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SDHD (NP_002993.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))
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别名
- SDHD
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背景
- This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants.,SDHD,CBT1,CII-4,CWS3,PGL,PGL1,QPs3,SDH4,cybS,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,SDHD
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分子量
- 9kDa/12kDa/15kDa/17kDa
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基因ID
- 6392
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UniProt
- O14521
抗原
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