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DBN1 抗体 (N-Term) (PE)

DBN1 适用: 人 FACS 宿主: 小鼠 Monoclonal DBN-N-03 PE
产品编号 ABIN1449752
发货至: 中国
  • 抗原 See all DBN1 抗体
    DBN1 (Drebrin 1 (DBN1))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-326, N-Term
    适用
    • 37
    • 20
    • 19
    • 1
    • 1
    宿主
    • 28
    • 9
    • 1
    小鼠
    克隆类型
    • 28
    • 10
    单克隆
    标记
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBN1 antibody is conjugated to PE
    应用范围
    • 35
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Size-Exclusion Chromatography and adjusted for direct use. No reconstitution is necessary
    免疫原
    Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326).
    克隆位点
    DBN-N-03
    亚型
    IgG2b
    Top Product
    Discover our top product DBN1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade protease free BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This products is photosensitive and should be protected from light.
  • 抗原
    DBN1 (Drebrin 1 (DBN1))
    别名
    Drebrin (DBN1 产品)
    别名
    D0S117E antibody, DBN1 antibody, LOC733967 antibody, drebrin 1 antibody, drebrin 1 S homeolog antibody, DBN1 antibody, Dbn1 antibody, dbn1.S antibody, dbn1 antibody
    背景
    Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.Synonyms: D0S117E, DBN-1, DBN1, DKFZp434D064, Developmentally-regulated brain protein, drebrin 1
    基因ID
    1627
    NCBI登录号
    NP_004386
    途径
    Maintenance of Protein Location
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