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DBN1 抗体 (AA 1-326)

DBN1 适用: 人 WB, FACS, CyTOF 宿主: 小鼠 Monoclonal DBN-N-03 unconjugated
产品编号 ABIN1558079
发货至: 中国
  • 抗原 See all DBN1 抗体
    DBN1 (Drebrin 1 (DBN1))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-326
    适用
    • 36
    • 20
    • 19
    • 1
    • 1
    宿主
    • 28
    • 8
    • 1
    小鼠
    克隆类型
    • 28
    • 9
    单克隆
    标记
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DBN1 antibody is un-conjugated
    应用范围
    • 34
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
    特异性
    The mouse monoclonal antibody DBN-N-03 recognizes drebrin, an approximately 100-125 kDa intracellular regulator of actin cytoskeleton.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
    克隆位点
    DBN-N-03
    亚型
    IgG2b
    Top Product
    Discover our top product DBN1 Primary Antibody
  • 应用备注
    Western blotting: Positive control: REH, Nalm-6, HEK293 cells.
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    DBN1 (Drebrin 1 (DBN1))
    别名
    Drebrin (DBN1 产品)
    别名
    D0S117E antibody, DBN1 antibody, LOC733967 antibody, drebrin 1 antibody, drebrin 1 S homeolog antibody, DBN1 antibody, Dbn1 antibody, dbn1.S antibody, dbn1 antibody
    背景
    Drebrin 1,Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.,DBN, D0S117E
    基因ID
    1627
    UniProt
    Q16643
    途径
    Maintenance of Protein Location
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